群组首页 » 时尚生活 » Innovation » 讨论区

[1]
 
发帖人   内容

TJKCB


发送悄悄话

第0楼

2020-01-31 13:12:42

 
Controlling this inflammatory CNS [引用]
PerspectiveNeuroscience

 

Monitoring neuronal health

See allHide authors and affiliations

Science  31 Jan 2020:
Vol. 367, Issue 6477, pp. 510-511
DOI: 10.1126/science.aba4472

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

 

Summary

Neurodegenerative disorders, most commonly stroke, Alzheimer's disease, and Parkinson's disease, affect millions of people worldwide (1). Despite their different etiologies, a frequent feature of neurodegenerative disorders is the persistent activation of the innate immune system (2). Controlling this inflammatory response in a way that positively affects clinical outcomes for cognition and behavior is a current major challenge and requires deeper understanding of the cellular and molecular mechanisms that govern neuroimmune interactions. On page 528 of this issue, Cserép et al. (3) identify a pathway through which microglia, the innate immune sensors of the central nervous system (CNS), monitor and influence neuronal health.

[返回顶部]
 
[1]